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pentobarbital will minimize the extent or effect of etravirine by affecting hepatic enzyme CYP2C9/ten metabolism. Use Warning/Observe.Contraindicated (one)pentobarbital decreases levels of panobinostat by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Robust CYP3A4 inducers can cut down panobinostat concentrations by ~70% a